Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma. Raquel Ordoñez, Marta Kulis, Nuria Russiñol et al. GENOME RES Aug 20 (2020). PubMed link

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard and high risk myeloma. Goicoechea I, Puig N, Cedena MT. et al. BLOOD Jul 21 (2020). PubMed link

Circulating tumor cells for comprehensive and multiregional non-invasive genetic characterization of multiple myeloma. Garcés JJ, Bretones G, Burgos L. et al.  LEUKEMIA Jun 1 (2020). PubMed link

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma. Perez C, Botta C, Zabaleta A. et al. BLOOD Jul 9; 136(2):199-209 (2020). PubMed link

Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma. Maia C, Puig N, Cedena MT. et al. BLOOD Jun 25; 135(26):2375-2387 (2020). PubMed link

Immunogenetic characterization of clonal plasma cells in systemic light-chain amyloidosis. Cuenca I, Alameda D, Sanchez-Vega B. et al. LEUKEMIA Mar 19 (2020). PubMed link

Characterization of freshly isolated mesenchymal stromal cells from healthy and multiple myeloma bone marrow: transcriptional modulation of the microenvironment. Alameda D, Saez B, Lara-Astiaso D. et al. HAEMATOLOGICA Jan 23 (2020). PubMed link

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma. Paiva B, Puig N, Cedena MT. et al. JOURNAL OF CLINICAL ONCOLOGY Mar 10; 38(8):784-792 (2020). PubMed link

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome. Duran-Ferrer M, Clot G. et al. NATURE CANCER Nov 02 (2020). PubMed link

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants. Rio-Machin, A., Vulliamy, T., Hug, N. et al. NATURE COMMUNICATIONS 11 (1): 1044 (2020). PubMed link

Immunogenetic characterization of clonal plasma cells in systemic light-chain amyloidosis. Cuenca I, Alameda D, Sanchez-Vega B, Gomez-Sanchez D, Alignani D, Lasa M, Onecha E, Lecumberri R, Prosper F, Ocio EM, González ME, García de Coca A, De La Rubia J, Gironella M, Palomera L, Oriol A, Casanova M, Cabañas V, Taboada F, Pérez-Montaña A, De Arriba F, Puig N, Carreño-Tarragona G, Barrio S, Enrique de la Puerta J, Ramirez-Payer A, Krsnik I, Bargay JJ, Lahuerta JJ, Mateos MV, San-Miguel JF, Paiva B, Lopez JM. LEUKEMIA Mar 19 (2020). PubMed link

Characterization of freshly isolated mesenchymal stromal cells from healthy and multiple myeloma bone marrow: transcriptional modulation of the microenvironment. Alameda D, Saez B, Lara-Astiaso D, Sarvide S, Lasa M, Alignani D, Rodriguez I, Garate S, Vilas A, Paiva B, Alfonso-Olmos M, Lamo de Espinosa JM, Prosper F, San Miguel JF, Maiso P. HAEMATOLOGICA Jan 23 (2020). PubMed link

Follicular Lymphoma. Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J. NATURE REVIEWS DISEASE  PRIMERS 5 (1): 83 (2019). PubMed link

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma. Paiva B, Puig N, Cedena MT, Rosiñol L, Cordón L, Vidriales MB, Burgos L, Flores-Montero J, Sanoja-Flores L, Lopez-Anglada L, Maldonado R, de la Cruz J, Gutierrez NC, Calasanz MJ, Martin-Ramos ML, Garcia-Sanz R, Martinez-Lopez J, Oriol A, Blanchard MJ, Rios R, Martin J, Martinez-Martinez R, Sureda A, Hernandez MT, de la Rubia J, Krsnik I, Moraleda JM, Palomera L, Bargay J, Van Dongen JJM, Orfao A, Mateos MV, Blade J, San-Miguel JF, Lahuerta JJ; GEM (Grupo Español de Mieloma)/PETHEMA (Programa Para el Estudio de la Terapéutica en Hemopatías Malignas) Cooperative Study Group. JOURNAL OF CLINICAL ONCOLOGY 38 (8): 784 (2019). PubMed link

Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination. Garcés JJ, Simicek M, Vicari M, Brozova L, Burgos L, Bezdekova R, Alignani D, Calasanz MJ, Growkova K, Goicoechea I, Agirre X, Pour L, Prosper F, Rios R, Martinez-Lopez J, Millacoy P, Palomera L, Del Orbe R, Perez-Montaña A, Garate S, Blanco L, Lasa M, Maiso P, Flores-Montero J, Sanoja-Flores L, Chyra Z, Vdovin A, Sevcikova T, Jelinek T, Botta C, El Omri H, Keats J, Orfao A, Hajek R, San-Miguel JF, Paiva B. LEUKEMIA 34 (2): 589 (2019). PubMed link

The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma. Moreno L, Perez C, Zabaleta A, Manrique I, Alignani D, Ajona D, Blanco L, Lasa M, Maiso P, Rodriguez I, Garate S, Jelinek T, Segura V, Moreno C, Merino J, Rodriguez-Otero P, Panizo C, Prosper F, San-Miguel JF, Paiva B. CLINICAL CANCER RESEARCH 25 (19): 3176 (2019). PubMed link

Flow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis. Puig N, Paiva B, Lasa M, Burgos L, Perez JJ, Merino J, Moreno C, Vidriales MB, Toboso DG, Cedena MT, Ocio EM, Lecumberri R, García de Coca A, Labrador J, Gonzalez ME, Palomera L, Gironella M, Cabañas V, Casanova M, Oriol A, Krsnik I, Pérez-Montaña A, de la Rubia J, de la Puerta JE, de Arriba F, Prosper F, Martinez-Lopez J, Lecrevisse Q, Verde J, Mateos MV, Lahuerta JJ, Orfao A, San Miguel JF. LEUKEMIA 33 (5): 1256 (2019). PubMed link