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News & Impact
The project (Key Goals)
Eloy Francisco Robles Cortes
We aim to clarify the signals that indicate the
transition of normal cells to a pre-malignant state, and full-blown disease
. We will also determine the
cellular complexity of MRD
Our key goals are to:
to detect, purify and characterise transformed cells at both pre-malignant and MRD stages.
including multi-omics characterisation of normal vs tumour vs immune cells from clinically-annotated patient populations.
Produce novel bioinformatic tools for
integrating multilayer data
for early intervention in pre-malignant and MRD disease states, as well as
novel therapeutic targets
humanised mouse models
of pre-malignant to full malignant disease.
tools and resources
will equip the scientific community to advance precision medicine in the three outlined blood cancers.
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